Coccidioidomycosis and blastomycosis: Advances in molecular diagnosis
نویسندگان
چکیده
منابع مشابه
Coccidioidomycosis and blastomycosis: advances in molecular diagnosis.
Clinical isolates of Coccidioides spp. and Blastomyces dermatitidis can be identified by chemiluminescent DNA probes and PCR assays targeting multicopy genes. In fixed tissue samples, cells of the two fungi are specified by in situ hybridization and PCR assays targeting 18S rDNA but sequencing of the products is mandatory. Nested PCR assays targeting genes encoding species- or genus-specific pr...
متن کاملRapid diagnosis of blastomycosis
A previously healthy man is hospitalized for a two-month illness characterized by productive cough, dyspnea, and weight loss. Empiric antibiotic therapy for community-acquired pneumonia failed to affect the symptoms. Six weeks later, the patient was hospitalized again, now with respiratory distress. Chest radiogram showed diffuse patchy nodular infiltrates. Antibiotics were modified but the pat...
متن کاملThe diagnosis of coccidioidomycosis
Until recently, culture, microscopy, and serology have been the available methods for the diagnosis of coccidioidomycosis. While Coccidioides is frequently isolated by culture, special precautions must be taken because of the risk of laboratory infection and because Coccidioides is on the Select Agent list. Serology is useful but the sensitivity remains lower than desired. A commercially availa...
متن کاملCoccidioidomycosis and Blastomycosis: Endemic Mycotic Co-Infections in the HIV Patient
Opportunistic fungal infections including aspergillosis species, candida species, and fusarium can be found in HIV-infected patients. Disseminated diseases due to endemic mycoses including histoplasmosis, coccidioidomycosis, and blastomycosis are all being reported among HIV patients who reside in the known endemic areas. However, in the non-endemic areas, or due to the rarity of these pathogen...
متن کاملTherapeutic effect of the triazole Bay R 3783 in mouse models of coccidioidomycosis, blastomycosis, and histoplasmosis.
A new triazole, Bay R 3783, was compared with ketoconazole, itraconazole, and fluconazole, which were given via the alimentary tract at three dosages, and amphotericin B, which was given at 1 mg/kg intraperitoneally, in murine models of the systemic mycoses coccidioidomycosis, histoplasmosis, and blastomycosis. In a pulmonary coccidioidomycosis model, Bay R 3783, fluconazole, and itraconazole w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEMS Immunology & Medical Microbiology
سال: 2005
ISSN: 0928-8244,1574-695X
DOI: 10.1016/j.femsim.2005.05.011